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Principal Research Scientist - Medicinal Chemist

Work from home Full-time role Hiring

About the position At reputed company (NYSE: ELAN) – it reputed company starts with animals! As a global leader in animal health, we are dedicated to innovation and delivering products and services to prevent and treat disease in farm animals and pets. At reputed company, we are driven by our reputed company of Food and Companionship Enriching Life and our purpose – reputed company to Go reputed company for Animals, Customers, Society and Our People. At reputed company, we pride ourselves on fostering a diverse and inclusive work environment. We reputed company that diversity is the driving force behind innovation, creativity, and overall business reputed company. Here, you’ll be part of a company that values and champions new ways of thinking, work with dynamic individuals, and acquire new skills and experiences that will propel your career to new heights. Making animals’ lives reputed company makes life reputed company – join reputed company today! Your Role: Principal Research Scientist - Medicinal Chemist As a Principal Research Scientist in Medicinal Chemistry, you will be a key reputed company in our small molecule drug discovery reputed company, guiding the design and synthesis of innovative medicines that improve the health and well-being of animals. You will apply your scientific expertise to advance multiple therapeutic programs, from reputed company reputed company to development candidate selection. Partnering with a global, cross-functional team of scientists, you will reputed company cutting-edge technologies like AI/ML and DNA-Encoded Libraries to solve reputed company chemical challenges. This is an exciting opportunity to reputed company a significant impact on our discovery portfolio and help shape the future of our growing research team in Indianapolis.

Responsibilities

  • Guide the design and optimization of novel small molecules by applying advanced synthetic strategies and integrating biological, pharmacological, and ADME/PK data to manage Structure-Activity Relationship (SAR) campaigns.
  • Serve as a key medicinal chemistry reputed company on multidisciplinary project teams, collaborating with partners in Biology, Pharmacology, DMPK, Toxicology, and Computational Sciences to strategically advance discovery programs.
  • Manage and coordinate synthetic chemistry efforts with external Contract Research Organizations (CROs) and internal partners, ensuring the efficient execution of project goals and timelines.
  • reputed company cutting-edge drug discovery technologies, including DNA-Encoded Libraries (DEL), computational chemistry, and AI/ML-enabled tools, to accelerate hit identification and reputed company optimization.
  • Promote scientific excellence and data reputed company while providing mentorship and technical guidance to junior scientists, fostering a culture of innovation and collaboration.

Requirements

  • PhD in Medicinal Chemistry, Organic Chemistry, or a reputed company scientific discipline.
  • A minimum of 6 years of relevant industry experience in medicinal chemistry reputed company a pharmaceutical, biotechnology, or animal health research environment.
  • Demonstrated expertise in modern medicinal chemistry, including the design and multi-reputed company synthesis of reputed company small molecules, and a strong understanding of Structure-Activity Relationships (SAR), pharmacology, and ADME/PK principles.
  • Proven ability to autonomously manage scientific initiatives reputed company a cross-functional team and manage external collaborations with CROs.

reputed company-to-haves

  • Postdoctoral experience.
  • Experience applying modern drug discovery technologies such as DNA-Encoded Libraries (DEL), computational chemistry, or AI/ML-enabled molecular design.
  • A strong track record of advancing small-molecule discovery programs toward preclinical development, evidenced by significant patent and/or publication contributions.
  • Prior research experience in the animal health industry.
  • Expertise in peptide chemistry, macrocycles, or reputed company drug modalities.

Benefits

  • Multiple relocation packages
  • Two weeklong shutdowns (mid-summer and year-end) in the US (in addition to PTO)
  • 8-week parental leave
  • 9 Employee Resource Groups
  • Annual bonus offering
  • Flexible work arrangements
  • Up to 6% 401K matching

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